GMPriority Pharma specialise only in liposomes and lipid encapsulation.
There is an art in creating effective liposomal delivery in supplements. Many factors play a role in proper liposomal nutritional manufacturing.
This process and technology is complicated and involves many steps to ensure proper stability, potency, compatibility and consistency.
Not all manufacturers standardise, research, validate or test these processes.
There is no standardisation or specific labelling requirements for liposomal manufacturers; finding the skills and experience necessary to ensure an effective formulation requires knowledge of the variables involved.
A small number of specialist nutritional supplement manufacturers are currently pioneering the benefits of this unique science. This new direction and employment of liposome science within the nutraceutical sector is due to the low absorption and bioavailability rates of some traditional food supplements.
The low oral bioavailability and absorption of many nutrients is clinically well documented; the natural encapsulation of lipophilic and hydrophilic nutrients within liposomes, therefore, improves stability of the encapsulated nutrient and improves absorption across intestinal epithelial membranes.
In order for liposomes to be effectively and efficiently absorbed into the cells, they need to be a certain size. If the liposome matrix is too large, it will not be absorbed and will instead be excreted. By utilising liposome encapsulation technology and reducing particle size to typically less than 200nm, nutrients can be absorbed into the cells for maximum efficiency.
Zeta potential is a measure of the magnitude of the electrostatic or charge repulsion/attraction between particles.
It is one of the fundamental parameters known to affect stability. Zeta potential measurement brings detailed insight into the causes of dispersion, aggregation or flocculation and can be applied to improve the formulation of liposomal formulations.