SAIFx® Technology
The discipline behind the science.
Controlled liposomal systems produced for integration into partner formulations and finished products.
SAIFx® Delivery Innovation
SAIFx® is GMPriority Pharma’s internal framework for designing, controlling and scaling liposomal systems across development and commercial production.
It defines how formulation composition, process parameters and analytical controls are aligned to support reproducible manufacturing and consistent product performance.
Why SAIFx® Exists
Liposomal systems introduce multiple interdependent variables, including lipid composition, particle size distribution, encapsulation efficiency and processing conditions.
In many development environments, these variables are addressed sequentially, leading to challenges during scale-up and commercial manufacture.
SAIFx® was developed to integrate these factors within a single structured framework, aligning development decisions with manufacturing requirements from the outset.
By applying defined parameters early, SAIFx® supports:
- Reduced process variability across scale
- Improved batch-to-batch consistency within defined ranges
- More predictable transfer from development into production
One technology.
Many applications.
The same delivery logic throughout.
What SAIFx® governs
SAIFx® defines how key technical variables are selected, controlled and monitored across development and manufacture.
This includes:
- Lipid system design
Selection of lipid composition aligned to active properties and delivery objectives - Particle size and dispersion behaviour
Control of size distribution and polydispersity index (PDI) through defined processing conditions - Encapsulation efficiency
Optimisation and verification under controlled formulation parameters - Processing conditions
Management of temperature, energy input, mixing and scale-dependent variables - Stability and handling conditions
Defined storage environments and evaluation protocols
Rather than prescribing a fixed format, SAIFx® provides a structured approach for managing these variables in line with ingredient, dosage form and commercial requirements.
Measured and controlled
Particle size distribution
Encapsulation efficiency
Stability under defined conditions
Critical process parameters
These measurements are applied within GMPriority Pharma’s manufacturing environment and verified through the VEREx® framework, which governs how process control and analytical oversight are implemented in practice.
Applied across development and manufacture
SAIFx® principles are applied across selected GMPriority Pharma programmes to ensure that formulation and manufacturing decisions remain aligned.
Stability, handling and scale considerations are incorporated during formulation design
Processing parameters are defined in relation to manufacturing equipment and conditions
Analytical measurements are used to verify system performance across development and production
This approach supports continuity between development and commercial manufacture, reducing the need for reformulation during scale-up.
Where SAIFx® is applied
SAIFx® underpins programmes where controlled liposomal structure and reproducible manufacture are critical.
- Branded ingredient collaborations requiring defined technical frameworks
- Liposomal formats where batch consistency and supply continuity are essential
- Development programmes progressing toward commercial-scale manufacture
Scientific Authentic Innovative Formulation
SAIFx® operates within GMPriority Pharma’s manufacturing environment, supporting structured execution rather than acting as a standalone technology.
